Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146459 | 0.94 | TLR7 (0.49) | TLR7ADORA2AADORA2B | |
| SCHEMBL4223870 | 0.92 | TLR7 (0.47) | TLR7 | |
| SCHEMBL20275365 | 0.91 | TLR7 (0.53) | TLR7 | |
| SCHEMBL14151403 | 0.90 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL2389535 | 0.89 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL2391153 | 0.89 | TLR7 (0.45) | TLR7 | |
| SCHEMBL1845303 | 0.88 | TLR7 (0.50) | TLR7 | |
| SCHEMBL728835 | 0.88 | TLR7 (0.50) | TLR7 | |
| SCHEMBL566897 | 0.88 | TLR7 (0.53) | TLR7 | |
| SCHEMBL4126699 | 0.87 | TLR7 (0.49) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018132-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-18 | — | — | WO | disclosed |