Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160208 | 0.87 | TSHR (0.73) | TSHRTHRBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL33467 | 0.87 | TSHR (0.48) | TSHRTHRBALDH1A1SMN1; SMN2MAPT | |
| Ethylene SCHEMBL2156738 | 0.85 | TSHR (0.70) | TSHRTHRBALDH1A1SMN1; SMN2MAPT | |
| Water SCHEMBL7715061 | 0.85 | TSHR (0.70) | TSHRTHRBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28322415 | 0.85 | TSHR (0.47) | TSHRTHRBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28322566 | 0.85 | TSHR (0.47) | TSHRTHRBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27805092 | 0.85 | TSHR (0.47) | TSHRTHRBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24562 | 0.85 | TSHR (1.00) | TSHRTHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL26811736 | 0.85 | TSHR (0.55) | TSHRTHRBALDH1A1MAPT | |
| SCHEMBL6350805 | 0.84 | TSHR (0.81) | TSHRTHRBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722826-B2 | Zwitterionic terpolymers, method of making and use on medical devices | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130296513-A1 | ZWITTERIONIC TERPOLYMERS, METHOD OF MAKING AND USE ON MEDICAL DEVICES | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2013-11-07 | — | — | US | disclosed |
| US-8431665-B2 | Zwitterionic terpolymers, method of making and use on medical devices | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100152402-A1 | ZWITERIONIC TERPOLYMERS, METHOD OF MAKING AND USE ON MEDICAL DEVICES | ABBOTT CARDIOVASCULAR SYSTEMS, INC. | 2010-06-17 | — | — | US | disclosed |
| US-7713541-B1 | Zwitterionic terpolymers, method of making and use on medical devices | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2010-05-11 | — | — | US | disclosed |
| EP-1348735-B1 | Block polymer composition comprising a methacrylic resin | KURARAY CO (JP) | 2008-07-02 | — | — | EP | disclosed |