Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 15/20 | 0.84 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043307 | 0.91 | ZAP70 (1.00) | ZAP70JAK1MAP4K1 | |
| SCHEMBL3360674 | 0.91 | ZAP70 (0.69) | ZAP70 | |
| SCHEMBL12928840 | 0.89 | ZAP70 (0.82) | ZAP70JAK1MAP4K1 | |
| SCHEMBL1049024 | 0.88 | ZAP70 (0.75) | ZAP70JAK1MAP4K1 | |
| SCHEMBL1046685 | 0.88 | ZAP70 (0.78) | ZAP70JAK1MAP4K1 | |
| SCHEMBL1048610 | 0.87 | ZAP70 (0.79) | ZAP70JAK1MAP4K1 | |
| SCHEMBL1046713 | 0.87 | ZAP70 (0.82) | ZAP70JAK1MAP4K1 | |
| SCHEMBL1047354 | 0.86 | ZAP70 (0.81) | ZAP70JAK1MAP4K1 | |
| SCHEMBL12928929 | 0.86 | ZAP70 (0.79) | ZAP70JAK1MAP4K1 | |
| SCHEMBL1047400 | 0.86 | ZAP70 (0.73) | ZAP70JAK1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238137-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2010-10-13 | — | — | EP | claimed |
| WO-2009097287-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-06 | — | — | WO | claimed |
| CN-101990539-A | Compounds and compositions as kinase inhibitors | IRM LLC | 2011-03-23 | — | — | CN | disclosed |