Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 13/20 | 0.56 |
| ▸ | DDO | Q99489 | 4/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360121 | 0.79 | DAO (0.54) | DAODDO | |
| SCHEMBL19127152 | 0.79 | DAO (0.44) | DAODDOIDH1ROCK1HRH4 | |
| SCHEMBL17913146 | 0.79 | DYRK1A (0.44) | DAODDOIDH1ROCK1HRH4 | |
| SCHEMBL17601628 | 0.78 | IDH1 (0.47) | DAODDOIDH1ROCK1HRH4 | |
| SCHEMBL17621792 | 0.77 | IDH1 (0.48) | IDH1ROCK1HRH4GRIN2DGRIN3B | |
| SCHEMBL19145075 | 0.76 | IDH1 (0.42) | DAODDOIDH1ROCK1HRH4 | |
| SCHEMBL21549760 | 0.76 | IDH1 (0.54) | IDH1HRH4 | |
| SCHEMBL21549765 | 0.76 | IDH1 (0.47) | DAODDOIDH1ROCK1HRH4 | |
| SCHEMBL3360471 | 0.74 | DAO (0.56) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20556189 | 0.73 | IDH1 (0.45) | DAODDOIDH1ROCK1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |