Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10265551 | 1.00 | AAK1 (0.48) | AAK1MMP1MMP2MMP3MMP8 | |
| SCHEMBL14923587 | 1.00 | AAK1 (0.48) | AAK1MMP1MMP2MMP3MMP8 | |
| SCHEMBL29323073 | 0.90 | SYK (0.42) | AAK1MMP1MMP2MMP3MMP8 | |
| SCHEMBL14923696 | 0.88 | SYK (0.48) | MMP1MMP2MMP3MMP8MMP13 | |
| SCHEMBL38666089 | 0.88 | SYK (0.48) | MMP1MMP2MMP3MMP8MMP13 | |
| SCHEMBL14923507 | 0.88 | SYK (0.48) | MMP1MMP2MMP3MMP8MMP13 | |
| SCHEMBL22806326 | 0.86 | ATM (0.44) | MMP1MMP2MMP3MMP8MMP13 | |
| SCHEMBL12719489 | 0.86 | ATM (0.44) | MMP1MMP2MMP3MMP8MMP13 | |
| SCHEMBL24074196 | 0.86 | MALT1 (0.49) | ATMMALT1AKT1KCNA5MEN1 | |
| SCHEMBL20757361 | 0.86 | ATM (0.42) | AAK1MMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |