Dimethylamine

Dimethylamine

SCHEMBL3361405

CCCC1CCC1.CNC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
SIGMAR1 Q99720 2/20 0.41
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
NOS3 P29474 5/20 0.34
NOS1 P29475 5/20 0.34
NOS2 P35228 5/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
FYN P06241 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130604 0.91
Methylethylamine SCHEMBL5949220 0.90 CYP1A2 (0.46) CYP1A2SIGMAR1CA1CA2CA4
Ammonia Solution, Strong SCHEMBL450376 0.88
Dimethylamine SCHEMBL5948494 0.88
Arsenic SCHEMBL3954753 0.88
Bromide SCHEMBL9835804 0.88
Hydrazine SCHEMBL7140405 0.86
SCHEMBL128592 0.85
Diethylamine SCHEMBL5949187 0.84 CYP1A2 (0.46) CYP1A2SIGMAR1CA1CA2CA4
Dimethylamine SCHEMBL5948617 0.84 CYP1A2 (0.73) CYP1A2SIGMAR1NOS1NOS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0018884-B1 PROCESS FOR THE PREPARATION OF TRIS(ETHER AMINES) AND SO OBTAINED TRIS(ETHER AMINES) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-11-04 EP claimed
EP-0018884-A1 Process for the preparation of tris(ether amines) and so obtained tris(ether amines) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1980-11-12 EP claimed
EP-1854638-B1 Reversible thermosensitive coloring material and reversible thermosensitive recording material using the same RICOH KK (JP) 2010-04-28 EP disclosed
US-7419934-B2 Reversible thermosensitive coloring material and reversible thermosensitive recording material using the reversible thermosensitive coloring material RICOH COMPANY LIMITED (JP) 2008-09-02 US disclosed
EP-1854638-A1 Reversible thermosensitive coloring material and reversible thermosensitive recording material using the same Ricoh Company, Ltd. (JP) 2007-11-14 EP disclosed
US-20070259782-A1 REVERSIBLE THERMOSENSITIVE COLORING MATERIAL AND REVERSIBLE THERMOSENSITIVE RECORDING MATERIAL USING THE REVERSIBLE THERMOSENSITIVE COLORING MATERIAL RICOH COMPANY, LIMITED (JP) 2007-11-08 US disclosed
US-7101940-B2 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-09-05 US disclosed
US-7034173-B2 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-04-25 US disclosed
US-6953829-B2 Catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2005-10-11 US disclosed
EP-1129065-B1 METHOD FOR PREPARING TRIS(ETHER-AMINE) RHODIA CHIMIE SA (FR) 2004-01-21 EP disclosed
US-20030144434-A1 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-07-31 US disclosed
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-01-16 US disclosed
EP-1129065-A1 METHOD FOR PREPARING TRIS(ETHER-AMINE) RHODIA CHIMIE (FR) 2001-09-05 EP disclosed
WO-2000027796-A1 METHOD FOR PREPARING TRIS(ETHER-AMINE) RHODIA CHIMIE (FR) 2000-05-18 WO disclosed
EP-0018884-B1 PROCESS FOR THE PREPARATION OF TRIS(ETHER AMINES) AND SO OBTAINED TRIS(ETHER AMINES) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-11-04 EP disclosed
EP-0018884-A1 Process for the preparation of tris(ether amines) and so obtained tris(ether amines) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1980-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144434-A1 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins CBR1, COX6C, CBR3 CYP1A2 26/4885SIGMAR1 657/4885CA1 473/4885
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins SCO2, CNOT1, CYC1 CYP1A2 348/4885SIGMAR1 1577/4885CA1 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.