⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584139 | 0.75 | — | — | |
| SCHEMBL1516769 | 0.72 | KDM4E (0.44) | — | |
| SCHEMBL1516784 | 0.72 | KDM4E (0.44) | — | |
| SCHEMBL261595 | 0.69 | — | — | |
| SCHEMBL28100631 | 0.67 | — | — | |
| SCHEMBL28487733 | 0.67 | — | — | |
| SCHEMBL1303156 | 0.67 | — | — | |
| SCHEMBL11080729 | 0.67 | — | — | |
| SCHEMBL9790071 | 0.67 | — | — | |
| SCHEMBL30383 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180264080-A1 | TOPICAL APPLICATIONS OF Kv1.3 CHANNEL BLOCKING PEPTIDES TO TREAT SKIN INFLAMMATION | KINETA ONE, LLC (US) | 2018-09-20 | — | — | US | disclosed |
| US-9937230-B2 | Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof | KINETA ONE, LLC (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160338967-A1 | SUSTAINED RELEASE DEPOT FORMULATIONS OF THERAPEUTIC PROTEINS, AND USES THEREOF | KINETA ONE, LLC (US) | 2016-11-24 | — | — | US | disclosed |
| EP-3086779-A2 | SUSTAINED RELEASE DEPOT FORMULATIONS OF THERAPEUTIC PROTEINS, AND USES THEREOF | Kineta One, LLC (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2016112208-A2 | TOPICAL APPLICATIONS OF KV1.3 CHANNEL BLOCKING PEPTIDES TO TREAT SKIN INFLAMMATION | KINETA ONE, LLP (US) | 2016-07-14 | — | — | WO | disclosed |
| US-20160151457-A1 | OPHTHALMIC USES OF TOXIN-BASED THERAPEUTIC PEPTIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | KINETA ONE, LLC (US) | 2016-06-02 | — | — | US | disclosed |
| EP-3024472-A2 | OPHTHALMIC USES OF TOXIN-BASED THERAPEUTIC PEPTIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | Kineta One, LLC (US) | 2016-06-01 | — | — | EP | disclosed |
| WO-2015100370-A2 | SUSTAINED RELEASE DEPOT FORMULATIONS OF THERAPEUTIC PROTEINS, AND USES THEREOF | KINETA ONE, LLC (US) | 2015-07-02 | — | — | WO | disclosed |
| WO-2015013330-A2 | OPHTHALMIC USES OF TOXIN-BASED THERAPEUTIC PEPTIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | KINETA ONE, LLC (US) | 2015-01-29 | — | — | WO | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| EP-1509537-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| EP-0676406-A3 | Process for preparing thiocarbonylmethanephosphonic acid diesters. | HOECHST AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0676407-A3 | Process for preparing thiocarbonylmethanephosphonic acid diesters. | HOECHST AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0676406-A2 | Process for preparing thiocarbonylmethanephosphonic acid diesters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |
| EP-0676406-A2 | Process for preparing thiocarbonylmethanephosphonic acid diesters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |
| EP-0676407-A2 | Process for preparing thiocarbonylmethanephosphonic acid diesters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |
| EP-0676407-A2 | Process for preparing thiocarbonylmethanephosphonic acid diesters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |
| WO-1995011911-A1 | BINDING COMPETENT OLIGOMERS CONTAINING UNSATURATED 3',5' AND 2',5' LINKAGES | GLAXO WELLCOME INC. (US) | 1995-05-04 | — | — | WO | disclosed |
| US-5098897-A | O-methyl thionoethanephosphonate derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |