Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954563 | 1.00 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL954564 | 1.00 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL954566 | 1.00 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL12946132 | 0.95 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL953459 | 0.94 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL953457 | 0.94 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL12946085 | 0.94 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL953458 | 0.94 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL3364479 | 0.94 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL955729 | 0.92 | TRPV1 (0.39) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238105-A2 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009096701-A2 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2009-08-06 | — | — | WO | disclosed |