Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.51 |
| ▸ | PIM1 | P11309 | 5/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.46 |
| ▸ | PIP4K2B | P78356 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362857 | 1.00 | PIM2 (0.51) | PIM2PIM1CSNK2A2CSNK2A1PIP4K2A | |
| SCHEMBL3363799 | 0.91 | PIM1 (0.50) | PIM2PIM1CSNK2A2CSNK2A1PIM3 | |
| SCHEMBL3363795 | 0.91 | PIM1 (0.50) | PIM2PIM1CSNK2A2CSNK2A1PIM3 | |
| SCHEMBL12989801 | 0.90 | PIM2 (0.62) | PIM2PIM1CSNK2A2CSNK2A1PIM3 | |
| SCHEMBL3366675 | 0.90 | PIM2 (0.62) | PIM2PIM1CSNK2A2CSNK2A1PIM3 | |
| SCHEMBL3366668 | 0.90 | PIM2 (0.62) | PIM2PIM1CSNK2A2CSNK2A1PIM3 | |
| SCHEMBL3362769 | 0.84 | PIM2 (0.48) | PIM2PIM1CSNK2A2CSNK2A1FLT3 | |
| SCHEMBL3363323 | 0.84 | PIM2 (0.44) | PIM2PIM1CSNK2A2CSNK2A1FLT3 | |
| SCHEMBL3363424 | 0.84 | IGF1R (0.45) | PIM2PIM1CSNK2A2CSNK2A1FLT3 | |
| SCHEMBL3363414 | 0.84 | IGF1R (0.45) | PIM2PIM1CSNK2A2CSNK2A1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| WO-2010148351-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148351-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | PIM2, PIM1, CDK2 | PIM2 1/4885PIM1 2/4885CSNK2A2 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.