⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R)-3-Hydroxybutanoate SCHEMBL60959 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1533862 | 1.00 | SLC22A6 (0.56) | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL28197574 | 1.00 | SLC22A6 (0.56) | — | |
| (R)-3-Hydroxybutanoate SCHEMBL29903959 | 1.00 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL1897117 | 1.00 | SLC22A6 (0.56) | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL2731 | 1.00 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL1881926 | 1.00 | SLC22A6 (0.56) | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL2749471 | 0.97 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL2342260 | 0.97 | — | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL9170835 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137663-A1 | ADMINISTRATION OF R-BETA-HYDROXYBUTYRATE SALT BLEND AND RELATED COMPOUNDS IN HUMANS | AXCESS GLOBAL SCIENCES LLC (US) | 2026-05-21 | — | — | US | claimed |
| US-12533346-B2 | Administration of berberine metabolites | AXCESS GLOBAL SCIENCES, LLC (US) | 2026-01-27 | — | — | US | claimed |
| US-12521378-B2 | Administration of R-beta-hydroxybutyrate salt blend and related compounds in humans | AXCESS GLOBAL SCIENCES, LLC (US) | 2026-01-13 | — | — | US | claimed |
| EP-4662192-A1 | MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS | Genomatica, Inc. (US) | 2025-12-17 | — | — | EP | claimed |
| US-12480061-B2 | System and method for liquid fuel production from carbonaceous materials using recycled conditioned syngas | THERMOCHEM RECOVERY INTERNATIONAL, INC. (US) | 2025-11-25 | — | — | US | claimed |
| US-20250302782-A1 | ADMINISTRATION OF BETA-HYDROXYBUTYRATE AND RELATED COMPOUNDS IN HUMANS FOR THE TREATMENT AND/OR PREVENTION OF RESPIRATORY ILLNESSES | AXCESS GLOBAL SCIENCES, LLC | 2025-10-02 | — | — | US | claimed |
| US-12409159-B2 | 3-hydroxybutyrate alone or in combination for use in the treatment of critical care treatment | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-09-09 | — | — | US | claimed |
| US-12396971-B2 | Administration of beta-hydroxybutyrate and related compounds in humans for the treatment and/or prevention of respiratory illnesses | AXCESS GLOBAL SCIENCES, LLC (US) | 2025-08-26 | — | — | US | claimed |
| CN-120129464-A | Flavonoid compound and application thereof | 弗门尼舍有限公司 | 2025-06-10 | — | — | CN | claimed |
| US-20250101472-A1 | GENETICALLY ENGINEERED BACTERIUM FOR THE PRODUCTION OF 3-HYDROXYBUTYRATE | Alliance for Energy Innovation, LLC | 2025-03-27 | — | — | US | claimed |
| US-20100209983-A1 | PREPARING METHOD FOR (S)-3HYDROXYBUTYRIC ACID AND (S)-3 HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM | LG-CHEM, LTD. (KR) | 2010-08-19 | — | — | US | claimed |
| CN-101802200-A | Preparing method for (s)-3-hydroxybutyric acid and (s)-3-hydroxybutyrate ester using recombinant microorganism | LG CHEMICAL LTD | 2010-08-11 | — | — | CN | claimed |
| EP-2176415-A1 | PREPARING METHOD FOR (S)-3-HYDROXYBUTYRIC ACID AND (S)-3-HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM | LG Chem. Ltd. (KR) | 2010-04-21 | — | — | EP | claimed |
| WO-2009020279-A1 | PREPARING METHOD FOR (S)-3-HYDROXYBUTYRIC ACID AND (S)-3-HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM | LG CHEM, LTD. (KR) | 2009-02-12 | — | — | WO | claimed |
| US-5461073-A | Using 3-hydroxybutyric acid and salts | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-10-24 | — | — | US | claimed |
| EP-0648490-A2 | Septicemia suppressing substitution fluid preparation | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-04-19 | — | — | EP | claimed |
| EP-0427396-B1 | Process for producing optically active fluorine-containing 3-hydroxybutyric acid esters | SHOWA SHELL SEKIYU (JP) | 1994-09-14 | — | — | EP | claimed |
| US-5292774-A | Energy source for patient unable to metabolize carbohydrates | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-08 | — | — | US | claimed |
| US-5191037-A | Polymers of 3-hydroxybutyric acid | DOI, YOSHIHARU (JP) | 1993-03-02 | — | — | US | claimed |
| EP-0232822-A1 | Process for preparing optically active fluorine-containing compounds | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-08-19 | — | — | EP | claimed |