Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362796 | 0.89 | LSS (0.66) | LSSMEN1KMT2A | |
| SCHEMBL3365198 | 0.88 | LSS (0.57) | LSSMEN1KMT2A | |
| SCHEMBL3364936 | 0.88 | LSS (0.49) | LSSMEN1KMT2A | |
| SCHEMBL3363725 | 0.87 | LSS (0.55) | LSSMEN1KMT2A | |
| SCHEMBL3367307 | 0.85 | LSS (0.49) | LSSMEN1KMT2A | |
| SCHEMBL3365253 | 0.85 | LSS (0.57) | LSSMEN1KMT2A | |
| SCHEMBL3365080 | 0.85 | LSS (0.48) | LSSMEN1KMT2A | |
| SCHEMBL7143601 | 0.84 | LSS (0.62) | LSSMEN1KMT2A | |
| SCHEMBL3365279 | 0.84 | LSS (0.63) | LSSMEN1KMT2A | |
| SCHEMBL3369265 | 0.83 | LSS (0.47) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303503-B1 | ANILINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-6683201-B2 | FOR THERAPY AND PROPHYLAXIS OF HYPERCHOLESTEROLEMIA, HYPERLIPEMIA, ARTERIOSCLEROSIS, VASCULAR DISEASES, MYCOSES, PARASITE INFECTIONS, GALLSTONES, TUMORS AND/OR HYPERPROLIFERATIVE DISORDERS, DIABETES | HOFFMANN-LA ROCHE INC. | 2004-01-27 | — | — | US | disclosed |
| EP-1303503-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006189-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |