Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720978 | 0.92 | DPP4 (0.47) | DPP4GAAMAPTAMY1ALMNA | |
| SCHEMBL3361667 | 0.92 | DPP4 (0.48) | DPP4GAAMAPTAMY1ALMNA | |
| SCHEMBL3364729 | 0.90 | DPP4 (0.50) | DPP4GAAMAPTAMY1ALMNA | |
| SCHEMBL3361788 | 0.89 | DPP4 (0.61) | DPP4GAAMAPTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3361781 | 0.88 | DPP4 (0.62) | DPP4GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL3363380 | 0.83 | DPP4 (0.49) | DPP4GAAMAPTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3365128 | 0.82 | DPP4 (0.50) | DPP4GAAMAPTKDM4EMEN1 | |
| SCHEMBL3364042 | 0.76 | DPP4 (0.44) | DPP4GAAMAPTLMNAKDM4E | |
| SCHEMBL8361366 | 0.76 | DPP4 (0.48) | DPP4MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL3359775 | 0.74 | DPP4 (0.59) | DPP4GAALMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |