Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365089 | 0.92 | HCRTR1 (0.43) | HCRTR1HCRTR2CHRM3 | |
| SCHEMBL3365182 | 0.91 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3362997 | 0.91 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL3365190 | 0.90 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3363382 | 0.89 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL3364134 | 0.88 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL3362248 | 0.87 | HCRTR1 (0.43) | HCRTR1HCRTR2CHRM3 | |
| SCHEMBL3360885 | 0.86 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3361281 | 0.84 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL3361276 | 0.84 | HCRTR1 (0.47) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155739-B1 | 2-CYCLOPROPYL-THIAZOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-10-06 | — | — | EP | claimed |