Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369420 | 0.87 | MEN1 (0.78) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL18315858 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL39206 | 0.78 | KMT2A (1.00) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2418987 | 0.76 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL18315859 | 0.76 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL503775 | 0.76 | MEN1 (0.75) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9617192 | 0.75 | MEN1 (0.79) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL22938990 | 0.75 | MEN1 (0.84) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL27913467 | 0.75 | MEN1 (0.89) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1963851 | 0.75 | MEN1 (0.70) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521798-B1 | SUNSCREENS | DSM IP ASSETS BV (NL) | 2010-01-27 | — | — | EP | disclosed |