Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.33 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28985816 | 0.98 | TSHR (0.41) | TSHRCA1CA2CA9PLA2G2C | |
| SCHEMBL11320138 | 0.82 | TSHR (0.43) | TSHRALDH1A1HPGDCA1CA2 | |
| SCHEMBL11312201 | 0.81 | TSHR (0.47) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL9235349 | 0.80 | TSHR (0.35) | TSHRALDH1A1HPGDCA1CA2 | |
| SCHEMBL3822338 | 0.78 | CA1 (0.38) | TSHRHPGDCA1CA2CA9 | |
| SCHEMBL3805260 | 0.78 | TSHR (0.34) | TSHRHPGDCA1CA2CA9 | |
| SCHEMBL28985856 | 0.76 | TSHR (0.35) | TSHRHPGDCA1CA2CA9 | |
| SCHEMBL28985829 | 0.76 | TSHR (0.35) | TSHRHPGDCA1CA2CA9 | |
| SCHEMBL1930609 | 0.76 | TSHR (0.41) | TSHRALDH1A1HPGDCA1CA2 | |
| SCHEMBL28985839 | 0.76 | TSHR (0.35) | TSHRHPGDCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145057-A1 | NOVEL PRODRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2010-06-10 | — | — | US | claimed |
| US-20050165206-A1 | Method for producing melt-stable homo- and copolyesters of cyclic esters and/or diesters | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2005-07-28 | — | — | US | claimed |
| CN-116390980-A | Flame-retardant polybutylene terephthalate resin composition and resin molded article | 宝理塑料株式会社 | 2023-07-04 | — | — | CN | disclosed |
| US-20210394486-A1 | ANTI-BLUSH AND CHEMICAL RESISTANT POLYESTER FILM | TORAY PLASTICS AMERICA INC (US) | 2021-12-23 | — | — | US | disclosed |
| US-11110688-B2 | Anti-blush and chemical resistant polyester film | TORAY PLASTICS (AMERICA), INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-9169360-B2 | Alkyl phosphinate polymer and methods for preparing and using the same | SHANGHAI HUIHAI CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2015-10-27 | — | — | US | disclosed |
| US-20150051328-A1 | ALKYL PHOSPHINATE POLYMER AND METHODS FOR PREPARING AND USING THE SAME | SHANGHAI HUIHAI CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2015-02-19 | — | — | US | disclosed |
| US-20060255494-A1 | Polymer composite material and process for producing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-11-16 | — | — | US | disclosed |
| EP-0248681-B1 | METHOD OF CLEANING THE INTERIOR OF POLYMERIZATION REACTOR | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-3957668-A | AIRCRAFT HYDRAULIC FLUID | MCDONNELL DOUGLAS CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145057-A1 | NOVEL PRODRUGS | UGT2B7, UGT1A1, UGT1A6 | TSHR 3135/4885ALDH1A1 221/4885HPGD 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.