Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 11/20 | 0.46 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608786 | 0.71 | COMT (0.61) | COMTALDH1A1MAPTHPGD | |
| SCHEMBL1608688 | 0.69 | COMT (0.58) | COMTALDH1A1MAPTHPGD | |
| SCHEMBL1608186 | 0.67 | COMT (0.73) | COMTALDH1A1 | |
| SCHEMBL1608762 | 0.65 | COMT (0.37) | COMT | |
| SCHEMBL1608348 | 0.65 | COMT (0.59) | COMTALDH1A1MAPTHPGD | |
| SCHEMBL3365763 | 0.64 | COMT (0.65) | COMTALDH1A1 | |
| SCHEMBL1608921 | 0.63 | COMT (0.59) | COMTALDH1A1MAPTHPGD | |
| SCHEMBL1609327 | 0.61 | COMT (0.69) | COMTALDH1A1MAPTHPGD | |
| SCHEMBL1608934 | 0.61 | COMT (0.83) | COMTMAPT | |
| SCHEMBL1609344 | 0.61 | COMT (0.53) | COMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910325-B1 | NEW PHARMACEUTICAL COMPOUNDS | ORION CORP (FI) | 2010-10-06 | — | — | EP | claimed |