Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.80 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366963 | 1.00 | HDAC1 (0.80) | HDAC1HDAC8HDAC2HDAC11HDAC6 | |
| SCHEMBL13227295 | 0.93 | HDAC1 (0.69) | HDAC1HDAC8HDAC2HDAC11HDAC6 | |
| SCHEMBL3368738 | 0.89 | HDAC1 (1.00) | HDAC1HDAC8HDAC2HDAC11HDAC6 | |
| SCHEMBL3368735 | 0.89 | HDAC1 (1.00) | HDAC1HDAC8HDAC2HDAC11HDAC6 | |
| SCHEMBL3372393 | 0.89 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL3372397 | 0.89 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL3369172 | 0.88 | HDAC1 (1.00) | HDAC1HDAC8HDAC2HDAC11HDAC6 | |
| SCHEMBL3369167 | 0.88 | HDAC1 (1.00) | HDAC1HDAC8HDAC2HDAC11HDAC6 | |
| SCHEMBL16788426 | 0.87 | HDAC1 (0.75) | HDAC1HDAC8HDAC2HDAC11HDAC6 | |
| SCHEMBL13226894 | 0.83 | HDAC1 (0.82) | HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673349-B1 | BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2010-06-30 | — | — | EP | claimed |