SCHEMBL3367050

SCHEMBL3367050

Cn1c(CN(Cc2ccccc2)Cc2ccccc2)nc2cc(C=CC(=O)NO)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 20/20 1.00
HDAC8 Q9BY41 8/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3367049 1.00 HDAC1 (1.00) HDAC1HDAC8
SCHEMBL18102190 0.91 HDAC1 (0.82) HDAC1HDAC8
SCHEMBL13118155 0.90 HDAC1 (0.82) HDAC1HDAC8
SCHEMBL3368483 0.88 HDAC1 (1.00) HDAC1HDAC8
SCHEMBL3368489 0.88 HDAC1 (1.00) HDAC1HDAC8
SCHEMBL3369131 0.87 HDAC1 (1.00) HDAC1HDAC8
SCHEMBL3369135 0.87 HDAC1 (1.00) HDAC1HDAC8
SCHEMBL3368459 0.85 HDAC1 (1.00) HDAC1HDAC8
SCHEMBL3366878 0.85 HDAC1 (1.00) HDAC1HDAC8
SCHEMBL3368463 0.85 HDAC1 (1.00) HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673349-B1 BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS S BIO PTE LTD (SG) 2010-06-30 EP claimed