Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433499 | 0.84 | TOP2A (0.38) | TOP2A | |
| Hydrochloric Acid SCHEMBL335992 | 0.83 | TOP2A (0.37) | TOP2A | |
| SCHEMBL3324013 | 0.81 | TOP2A (0.33) | TOP2A | |
| SCHEMBL12746550 | 0.81 | TOP2A (0.36) | TOP2A | |
| SCHEMBL3366842 | 0.81 | TOP2A (0.54) | TOP2A | |
| SCHEMBL3324663 | 0.78 | TOP2A (0.35) | TOP2A | |
| SCHEMBL3328189 | 0.78 | TOP2A (0.40) | TOP2A | |
| SCHEMBL10128161 | 0.72 | — | — | |
| SCHEMBL10128141 | 0.72 | KCNA3 (0.46) | TOP2A | |
| SCHEMBL3330445 | 0.72 | TOP2A (0.53) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137196-B1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2010-10-06 | — | — | EP | disclosed |