Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108403 | 0.91 | MLLT1 (0.47) | NPC1RAB9AS1PR1SMYD3MLLT1 | |
| Hydrochloric Acid SCHEMBL28847292 | 0.89 | MLLT1 (0.46) | NPC1RAB9AS1PR1SMYD3MLLT1 | |
| SCHEMBL25213670 | 0.84 | NPC1 (0.54) | NPC1RAB9AS1PR1ALDH1A1MLLT1 | |
| SCHEMBL30424616 | 0.83 | NPC1 (0.56) | NPC1RAB9AS1PR1ALDH1A1MLLT1 | |
| SCHEMBL27028220 | 0.82 | CNR2 (0.47) | NPC1RAB9AS1PR1CHRNB2CHRNA7 | |
| Cyclopropane Carboxylic Acid SCHEMBL27544465 | 0.81 | CHRNA4 (0.42) | NPC1RAB9AALDH1A1CHRNA4KMT2A | |
| Hydrochloric Acid SCHEMBL693291 | 0.79 | SMYD3 (0.59) | NPC1RAB9AS1PR1SMYD3MLLT1 | |
| SCHEMBL3347092 | 0.79 | NPC1 (0.47) | NPC1RAB9AS1PR1GAADGAT1 | |
| SCHEMBL10192549 | 0.77 | HTT (0.50) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL3334156 | 0.76 | EPHX1 (0.46) | NPC1RAB9AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653125-B2 | Cyclohexane derivative having NPY Y5 receptor antagonism | SHIONOGI CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| US-20120004227-A1 | CYCLOHEXANE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISM | SHIONOGI & CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004227-A1 | CYCLOHEXANE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISM | NPY5R, NPY1R, NPY2R | NPC1 2045/4885RAB9A 2887/4885S1PR1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.