Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | F7 | P08709 | 6/20 | 0.58 |
| ▸ | F3 | P13726 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | PPARD | Q03181 | 4/20 | 0.58 |
| ▸ | PPARA | Q07869 | 4/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30902072 | 0.95 | FFAR1 (0.65) | FFAR1FFAR4F7F3PPARG | |
| SCHEMBL3683366 | 0.95 | FFAR1 (0.65) | FFAR1FFAR4F7F3PPARG | |
| SCHEMBL162101 | 0.95 | FFAR1 (0.65) | FFAR1FFAR4F7F3PPARG | |
| Ethylene SCHEMBL10697177 | 0.92 | FFAR1 (0.61) | FFAR1FFAR4F7F3PPARG | |
| Ethylene Glycol SCHEMBL20678202 | 0.92 | FFAR1 (0.61) | FFAR1FFAR4F7F3PPARG | |
| SCHEMBL30951731 | 0.92 | FFAR1 (0.65) | FFAR1FFAR4ALDH1A1F7F3 | |
| Oleic Acid SCHEMBL29894126 | 0.86 | FFAR1 (0.76) | FFAR1FFAR4ALDH1A1F7F3 | |
| SCHEMBL30457930 | 0.86 | FFAR1 (0.71) | FFAR1FFAR4F7F3PPARG | |
| SCHEMBL30458046 | 0.86 | FFAR1 (0.71) | FFAR1FFAR4F7F3PPARG | |
| SCHEMBL10081556 | 0.86 | FFAR1 (0.71) | FFAR1FFAR4F7F3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303596-B1 | MORPHOLINO ANTISENSE OLIGOMERS AS ENZYME INHIBITORS FOR IMPROVING PHARMACOKINETICS OF A DRUG | UNIV NEBRASKA (US) | 2010-09-15 | — | — | EP | disclosed |
| US-20040229829-A1 | Enzyme inhibitors for metabolic redirection | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2004-11-18 | — | — | US | disclosed |
| US-6673778-B1 | ADMINISTERING TRANSDERMALLY MORPHOLINO ANTISENSE OLIGOMER TO REDUCE EXPRESSION OF CYTOCHROME P450 ENZYME THAT CATALYZES METABOLISM OF DRUG, BY HYBRIDIZING TO TARGET RNA MOLECULE WHICH ENCODES ENZYME, THUS INHIBITING METABOLISM OF DRUG | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2004-01-06 | — | — | US | disclosed |
| EP-1303596-A2 | ANTISENSE ENZYME INHIBITORS FOR IMPROVING PHARMACOKINETICS OF A DRUG | Avi Biopharma, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001087286-A2 | ANTISENSE ENZYME INHIBITORS FOR IMPROVING PHARMACOKINETICS OF A DRUG | AVI BIOPHARMA, INC. (US) | 2001-11-22 | — | — | WO | disclosed |