Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368683 | 0.81 | EGLN1 (1.00) | EGLN1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL3371492 | 0.72 | EGLN1 (0.64) | EGLN1L3MBTL1NAMPTPKMSMN1; SMN2 | |
| SCHEMBL3370079 | 0.70 | EGLN1 (1.00) | EGLN1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3368198 | 0.66 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL3370372 | 0.66 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL3368312 | 0.65 | EGLN1 (0.77) | EGLN1ALDH1A1 | |
| SCHEMBL10854541 | 0.64 | QPCT (0.65) | L3MBTL1NAMPTALDH1A1CYP19A1MEN1 | |
| SCHEMBL3367974 | 0.64 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL13472650 | 0.63 | KDM4E (0.67) | L3MBTL1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10819292 | 0.62 | SMN1; SMN2 (0.71) | L3MBTL1NAMPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |