Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611510 | 1.00 | ACE (0.74) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| SCHEMBL10974032 | 0.93 | ACE (0.65) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| SCHEMBL10610279 | 0.89 | ACE (0.60) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| SCHEMBL10971911 | 0.89 | ACE (0.70) | ACELMNASMN1; SMN2ACE2 | |
| Hydrochloric Acid SCHEMBL10611825 | 0.88 | ACE (0.59) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| SCHEMBL10784326 | 0.86 | ACE (0.66) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| SCHEMBL682328 | 0.86 | ACE (0.83) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| SCHEMBL10783195 | 0.86 | ACE (0.65) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| Trifluoroacetic Acid SCHEMBL10971638 | 0.86 | ACE (0.70) | ACELMNASMN1; SMN2ACE2ABCB11 | |
| Maleic Acid SCHEMBL10612014 | 0.85 | SMN1; SMN2 (0.62) | ACELMNASMN1; SMN2ACE2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679303-B1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | KANEKA CORP (JP) | 2010-09-15 | — | — | EP | disclosed |
| EP-1679303-A1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | Kaneka Corporation (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-0903337-B1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORP (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-6118010-A | CATALYTIC REDUCTION OF THE 1-ALKOXYCARBONYL-3-OXO-3-PHENYLPROPYL DERIVATIVE | KANEKA CORPORATION (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0903337-A1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-4528282-A | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-07-09 | — | — | US | disclosed |
| US-4442030-A | ARALKYLATION WITH BENZOYLACRYLIC ACID, HYDROGENATION, ESTERIFICATION | MERCK & CO., INC. (US) | 1984-04-10 | — | — | US | disclosed |