Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369151 | 1.00 | HDAC1 (1.00) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL18102185 | 0.89 | HDAC1 (0.81) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3368667 | 0.86 | HDAC1 (1.00) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3368669 | 0.86 | HDAC1 (1.00) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL13118140 | 0.83 | HDAC1 (0.72) | HDAC1HDAC8HDAC6 | |
| SCHEMBL3368809 | 0.81 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL3369171 | 0.81 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL3367270 | 0.80 | HDAC1 (1.00) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3367267 | 0.80 | HDAC1 (1.00) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3368979 | 0.80 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673349-B1 | BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2010-06-30 | — | — | EP | claimed |