Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.89 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.78 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.78 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.78 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.78 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.78 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.78 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.78 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369380 | 1.00 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3369062 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3369058 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3368922 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3368919 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3372830 | 0.92 | HDAC1 (0.93) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3372833 | 0.92 | HDAC1 (0.93) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3369088 | 0.91 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL8291358 | 0.91 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL3369085 | 0.91 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673349-B1 | BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2010-06-30 | — | — | EP | claimed |