Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.57 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369583 | 0.83 | SCD (0.75) | SCD | |
| SCHEMBL3369591 | 0.80 | SCD (0.64) | SCDMAPK14 | |
| SCHEMBL3370621 | 0.77 | SCD (0.71) | SCD | |
| SCHEMBL3373774 | 0.76 | SCD (0.71) | SCD | |
| SCHEMBL3373522 | 0.76 | SCD (0.57) | SCD | |
| SCHEMBL27946824 | 0.74 | SCD (0.54) | SCD | |
| SCHEMBL3368056 | 0.73 | SCD (0.73) | SCD | |
| SCHEMBL3367908 | 0.73 | SCD (1.00) | SCD | |
| SCHEMBL3370625 | 0.73 | SCD (0.61) | SCD | |
| SCHEMBL244461 | 0.71 | SCD (0.78) | SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029572-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-03 | — | — | EP | disclosed |