⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25697034 | 0.89 | — | — | |
| SCHEMBL7436238 | 0.89 | — | — | |
| SCHEMBL8184317 | 0.87 | DPP7 (0.52) | — | |
| SCHEMBL7473497 | 0.83 | DPP7 (0.31) | — | |
| SCHEMBL2297128 | 0.79 | EPHX2 (0.34) | — | |
| SCHEMBL19753009 | 0.76 | EPHX1 (0.40) | — | |
| SCHEMBL15715697 | 0.75 | DPP7 (0.39) | — | |
| SCHEMBL4019293 | 0.74 | — | — | |
| SCHEMBL29427825 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL15670961 | 0.73 | DPP7 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190289-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | Intervet International B.V. (NL) | 2010-06-02 | — | — | EP | claimed |
| WO-2009024541-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. (NL) | 2009-02-26 | — | — | WO | claimed |
| EP-3473101-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS FOR FELINES | Intervet International B.V. (NL) | 2019-04-24 | — | — | EP | disclosed |
| EP-2417140-B1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2014-11-26 | — | — | EP | disclosed |
| EP-2190289-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | Intervet International B.V. (NL) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009024541-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. (NL) | 2009-02-26 | — | — | WO | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |