SCHEMBL3369679

SCHEMBL3369679

CC(C)N1CCC(NC(=O)c2nc3c(OC(=O)O)cccc3n2Cc2n[nH]c3ccc(Cl)cc23)CC1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 16/20 0.45
DYRK1A Q13627 4/20 0.44
WNT1 P04628 3/20 0.44
F2 P00734 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1382199 0.89 F10 (0.47) F10DYRK1AWNT1F2
SCHEMBL3371313 0.82 F10 (0.57) F10F2
SCHEMBL3368985 0.77 F10 (0.64) F10F2
SCHEMBL3374120 0.71 F10 (0.64) F10F2
SCHEMBL1380010 0.70 F10 (0.59) F10F2
SCHEMBL3369662 0.70 F10 (0.53) F10F2
SCHEMBL3373205 0.70 F10 (0.75) F10F2
SCHEMBL1380973 0.69 F10 (0.62) F10F2
SCHEMBL1380548 0.68 F10 (0.65) F10F2
SCHEMBL1383452 0.68 F10 (0.63) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636216-B1 BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI AVENTIS DEUTSCHLAND (DE) 2010-07-21 EP claimed