SCHEMBL3369786 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	9/20	0.44

▸	SLC6A2	P23975	1/20	0.33

▸	SLC6A4	P31645	1/20	0.33

▸	NPC1	O15118	1/20	0.31

▸	HSP90AA1	P07900	1/20	0.31

▸	RAB9A	P51151	1/20	0.31

▸	ACSS2	Q9NR19	2/20	0.31

▸	MC4R	P32245	2/20	0.31

▸	KIF11	P52732	1/20	0.31

▸	NLRP3	Q96P20	1/20	0.31

▸	F2	P00734	1/20	0.30

▸	KLK1	P06870	1/20	0.30

▸	REN	P00797	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1380995	0.80	F10 (0.65)	F10F2KLK1
SCHEMBL3368844	0.74	F10 (0.65)	F10F2KLK1
SCHEMBL3373199	0.73	F10 (0.67)	F10F2KLK1
SCHEMBL3369797	0.70	F10 (0.64)	F10F2KLK1
SCHEMBL3367396	0.69	F10 (0.64)	F10F2KLK1
SCHEMBL4606185	0.68	F10 (0.43)	F10F2KLK1
SCHEMBL1378415	0.67	F10 (0.67)	F10F2KLK1
SCHEMBL1381864	0.67	F10 (0.79)	F10F2KLK1
SCHEMBL3374386	0.66	F10 (0.64)	F10F2KLK1
SCHEMBL4606656	0.65	F10 (0.44)	F10F2KLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1636216-B1	BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS	SANOFI AVENTIS DEUTSCHLAND (DE)	2010-07-21	—	—	EP	claimed