Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.71 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368158 | 0.83 | EGLN1 (1.00) | EGLN1SMN1; SMN2 | |
| SCHEMBL3369495 | 0.80 | EGLN1 (0.70) | EGLN1 | |
| SCHEMBL3371937 | 0.80 | EGLN1 (0.73) | EGLN1 | |
| SCHEMBL3370648 | 0.79 | EGLN1 (0.66) | EGLN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3369243 | 0.78 | EGLN1 (0.96) | EGLN1 | |
| SCHEMBL3367930 | 0.78 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL3371510 | 0.78 | EGLN1 (0.70) | EGLN1 | |
| SCHEMBL3368117 | 0.78 | EGLN1 (0.75) | EGLN1 | |
| SCHEMBL3371387 | 0.78 | EGLN1 (0.83) | EGLN1 | |
| SCHEMBL3368332 | 0.77 | EGLN1 (0.72) | EGLN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |