Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.64 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372872 | 0.94 | F10 (0.59) | F10F2KLK1 | |
| SCHEMBL3371347 | 0.89 | F10 (0.80) | F10F2KLK1 | |
| SCHEMBL1382031 | 0.89 | F10 (0.80) | F10F2KLK1 | |
| SCHEMBL3371039 | 0.86 | F10 (0.59) | F10F2 | |
| SCHEMBL3369688 | 0.85 | F10 (0.71) | F10F2KLK1 | |
| SCHEMBL3368882 | 0.84 | F10 (0.73) | F10F2KLK1 | |
| SCHEMBL3371719 | 0.82 | F10 (0.76) | F10F2KLK1 | |
| SCHEMBL3369183 | 0.81 | F10 (0.64) | F10F2KLK1 | |
| SCHEMBL3367729 | 0.81 | F10 (0.54) | F10F2KLK1 | |
| SCHEMBL3370906 | 0.80 | F10 (0.62) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | claimed |