SCHEMBL337031

SCHEMBL337031

O=C(O)CCCCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
LMNA P02545 2/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43
PTGS1 P23219 4/20 0.40
PTGS2 P35354 4/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
GAA P10253 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
F13A1 P00488 3/20 0.38
GPR84 Q9NQS5 3/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
ALDH1A1 P00352 2/20 0.37
PPARG P37231 3/20 0.36
PPARD Q03181 3/20 0.36
PPARA Q07869 3/20 0.36
HDAC11 Q96DB2 2/20 0.36
TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL336568 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL336648 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL1230060 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL25406852 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL25408775 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL25408793 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL25408300 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL25407766 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL905403 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1
SCHEMBL337556 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115856286-B Preparation method of high-stability magnetic beads 中元汇吉生物技术股份有限公司 2025-03-07 CN claimed
CN-117085167-A Medical adhesive and preparation method thereof 海宁侏罗纪生物科技有限公司 2023-11-21 CN claimed
CN-117085168-A Medical adhesive and preparation method thereof 海宁侏罗纪生物科技有限公司 2023-11-21 CN claimed
CN-115856286-A Preparation method of high-stability magnetic beads 中元汇吉生物技术股份有限公司 2023-03-28 CN claimed
US-20220354957-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF TWINPIG BIOLAB, INC. (KR) 2022-11-10 US claimed
CN-113827766-B Drug-loaded surgical sealant and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2022-05-24 CN claimed
US-20190345669-A1 Modifying Natural Feathers For Use in Sporting Goods DURABIRD PTE LTD (SG) 2019-11-14 US claimed
US-10415180-B2 Modifying natural feathers for use in sporting goods DURABIRD LLC 2019-09-17 US claimed
US-20190177909-A1 Modifying Natural Feathers For Use in Sporting Goods DURABIRD LLC 2019-06-13 US claimed
CN-109248326-A A kind of Bone targeting nanoparticle delivery system and preparation method thereof 深圳先进技术研究院 2019-01-22 CN claimed
CN-109072482-A MULTIVALENT GLYCAN MICROARRAY PLATFORM Z生物科技有限公司 2018-12-21 CN claimed
CN-103097550-B Method for isolating proteins binding to any type of nucleic acid sequence of interest NATIONAL RESEARCH CENTER (FR) 2016-03-16 CN claimed
CN-103145832-B Synthetic method of cephalosporin drugs general artificial antigen UNIV JIANGNAN 2015-01-21 CN claimed
CN-103145832-A Synthetic method of cephalosporin drugs general artificial antigen UNIV JIANGNAN 2013-06-12 CN claimed
EP-2408470-A1 Soluble non-depot insulin conjugates and uses thereof Smartcells, Inc. (US) 2012-01-25 EP claimed
WO-2010107520-A1 SOLUBLE NON-DEPOT INSULIN CONJUGATES AND USES THEREOF SMARTCELLS, INC. (US) 2010-09-23 WO claimed
CN-101535808-A Method for purifying at least one target substance to be identified JOCHEN PETER (DE) 2009-09-16 CN claimed
US-7470469-B1 Medical device having surface modification with superoxide dismutase mimic ADVANCED CARDIOVASCULAR SYSTEMS INC. (US) 2008-12-30 US claimed
US-12276654-B2 Chemical probe-dependent evaluation of protein activity and uses thereof THE UNIVERSITY OF CHICAGO (US) 2025-04-15 US disclosed
WO-1985001354-A1 DETECTING AN IMMUNOLOGICAL REACTION WITH ACTIVATED RED BLOOD CELLS (ERYTHROCYTES) IMMUCOR, INC. (US) 1985-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12276654-B2 Chemical probe-dependent evaluation of protein activity and uses thereof GBA3, ACP1, GUSB TSHR 3511/4885LMNA 3601/4885NFKB1 3414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.