SCHEMBL3370677

SCHEMBL3370677

CC[C@@H]1C[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(C)=O)c2cc(C(F)(F)F)ccc2N1OC(=O)OC(C)C

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6586111 0.92 CETP (0.67) CETP
SCHEMBL3375812 0.92 CETP (0.68) CETP
SCHEMBL6587928 0.90 CETP (0.66) CETP
SCHEMBL6588727 0.90 CETP (0.77) CETP
SCHEMBL6587310 0.89 CETP (0.64) CETP
SCHEMBL6588384 0.88 CETP (0.59) CETP
SCHEMBL992623 0.87 CETP (1.00) CETP
SCHEMBL30211969 0.87 CETP (1.00) CETP
SCHEMBL14015281 0.87 CETP (1.00) CETP
SCHEMBL1436500 0.87 CETP (1.00) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1855652-B1 DRYING OF DRUG-CONTAINING PARTICLES BEND RES INC (US) 2015-12-02 EP claimed
EP-1404302-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING ADSORBATES OF AMORPHOUS DRUG PFIZER PROD INC (US) 2010-11-03 EP claimed
EP-1114032-B1 4-AMINO SUBSTITUTED-2-SUBSTITUTED-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS PFIZER PROD INC (US) 2004-06-02 EP claimed