Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.63 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.63 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366040 | 0.85 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL3368150 | 0.82 | HCRTR1 (0.67) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL3368066 | 0.80 | HCRTR1 (0.71) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL3366784 | 0.79 | HCRTR1 (0.65) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL3367057 | 0.79 | HCRTR1 (0.65) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL3366720 | 0.79 | HCRTR1 (0.65) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL3366800 | 0.79 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL3366717 | 0.78 | HCRTR1 (0.68) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL3364799 | 0.78 | HCRTR1 (0.64) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL17063859 | 0.77 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532141-B1 | 2-PYRROLIDIN-2-YL- [1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS | GRUENENTHAL GMBH (DE) | 2010-10-13 | — | — | EP | disclosed |