Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 16/20 | 0.69 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369826 | 0.99 | EGLN1 (0.70) | EGLN1IKBKBMKNK1MKNK2SCN9A | |
| SCHEMBL3368851 | 0.92 | EGLN1 (0.68) | EGLN1 | |
| SCHEMBL3367733 | 0.91 | EGLN1 (0.67) | EGLN1 | |
| SCHEMBL3370726 | 0.86 | EGLN1 (0.65) | EGLN1MKNK1MKNK2SCN9A | |
| SCHEMBL3369366 | 0.86 | EGLN1 (0.65) | EGLN1 | |
| SCHEMBL3367957 | 0.83 | EGLN1 (0.63) | EGLN1 | |
| SCHEMBL3369432 | 0.82 | EGLN1 (0.98) | EGLN1 | |
| SCHEMBL3372156 | 0.82 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL3403512 | 0.81 | EGLN1 (0.72) | EGLN1 | |
| SCHEMBL3369074 | 0.81 | EGLN1 (1.00) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |