Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368996 | 0.93 | F10 (0.52) | F10F2ALDH1A1LMNARAB9A | |
| SCHEMBL3368985 | 0.90 | F10 (0.64) | F10F2 | |
| SCHEMBL3369485 | 0.88 | F10 (0.52) | F10F2ALDH1A1LMNARAB9A | |
| SCHEMBL3369922 | 0.86 | F10 (0.52) | F10F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1382441 | 0.84 | F10 (0.48) | F10F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3374120 | 0.84 | F10 (0.64) | F10F2 | |
| SCHEMBL1380548 | 0.80 | F10 (0.65) | F10F2 | |
| SCHEMBL1383452 | 0.80 | F10 (0.63) | F10F2 | |
| SCHEMBL1379117 | 0.78 | F10 (0.61) | F10F2 | |
| SCHEMBL1381138 | 0.78 | F10 (0.67) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | claimed |