Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17825462 | 0.80 | P4HTM (0.54) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL1888804 | 0.77 | CPA1 (0.53) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL67234 | 0.71 | EPHX1 (0.71) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL599399 | 0.71 | EPHX1 (0.71) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL3079795 | 0.71 | EPHX1 (0.71) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL1127361 | 0.70 | CYP1A2 (0.53) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| Hydrochloric Acid SCHEMBL933353 | 0.70 | EPHX1 (0.69) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL11204799 | 0.68 | CPA1 (0.43) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL11551047 | 0.68 | P4HTM (0.46) | P4HTMCPA1CYP1A2EPHX1ALPI | |
| SCHEMBL17825496 | 0.68 | CPA1 (0.50) | P4HTMCPA1CYP1A2EPHX1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | S1PR1, S1PR5, S1PR3 | P4HTM 1938/4885CPA1 380/4885CYP1A2 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.