SCHEMBL33720

SCHEMBL33720

Cc1nn(CCO)c(N)c1N

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.44
GAA P10253 7/20 0.43
CYP1A2 P05177 1/20 0.41
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 1/20 0.37
GFER P55789 1/20 0.36
SLC2A1 P11166 1/20 0.35
MAPT P10636 1/20 0.34
BRD4 O60885 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NR1I2 O75469 1/20 0.32
AHR P35869 1/20 0.32
MAPK8 P45983 1/20 0.31
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6278290 0.98 HTT (0.42) HTTGAACYP1A2ALDH1A1KDM4E
SCHEMBL2981441 0.88 HPGD (0.40) HTTGAACYP1A2ALDH1A1KDM4E
SCHEMBL12479057 0.83 GAA (0.56) HTTGAACYP1A2ALDH1A1KDM4E
SCHEMBL12335146 0.83 CYP1A2 (0.41) HTTGAACYP1A2ALDH1A1KDM4E
SCHEMBL29175218 0.83 GAA (0.46) HTTGAAALDH1A1KDM4EGFER
SCHEMBL6731431 0.81 ADORA2A (0.46) GAAALDH1A1KDM4EGFERSLC2A1
SCHEMBL3201118 0.77 GAA (0.39) HTTGAACYP1A2ALDH1A1KDM4E
SCHEMBL2953524 0.77 CYP1A2 (0.42) HTTCYP1A2ALDH1A1MAPTNR1I2
SCHEMBL5767901 0.76 TLR8 (0.37) GAAALDH1A1KDM4EGFER
SCHEMBL2927471 0.76 GAA (0.37) GAAALDH1A1KDM4EGFERSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2716 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
EP-4552630-A1 RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD Wella Operations US, LLC (US) 2025-05-14 EP claimed
WO-2025043531-A1 COLORANT COMPOSITION FOR DYEING KERATIN FIBERS AND KIT COMPRISING THE SAME L'OREAL (FR) 2025-03-06 WO claimed
WO-2025008339-A1 OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2025-01-09 WO claimed
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20200392088-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-17 US claimed
EP-3142638-B1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER OREAL (FR) 2020-08-12 EP claimed
EP-3464247-B1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES OREAL (FR) 2020-03-11 EP claimed
US-9993409-B2 Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler L'OREAL (FR) 2018-06-12 US claimed
US-20170087075-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER L'OREAL (FR) 2017-03-30 US claimed
US-6241784-B1 COSMETICS OR SKIN COMPOSITION FOR TREATING FIBERS L'OREAL S.A. (FR) 2001-06-05 US claimed
US-6228129-B1 OXIDATION BASE, CATIONIC DIRECT DYE AND AN ENZYME OF 2-ELECTRON OXIDOREDUCTASES IN THE PRESENCE OF A DONOR FOR THE ENZYME L'OREAL S.A. (FR) 2001-05-08 US claimed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1068860-A1 Dyeing composition containing 1-acetoxy naphthalene, two oxidation bases and a coupling agent L'OREAL (FR) 2001-01-17 EP claimed
US-6099592-A SPECIFIED 3-SUBSTITUTED 4,5-DIAMINOPYRAZOLES SUCH AS 1-BENZYL-4,5-DIAMINO-3-METHYLPYRAZOLE AS OXIDATION DYE PRECURSORS; USE TO OBTAIN DYE COMPOSITIONS LEADING TO STRONG COLORATIONS, IN SHADES RANGING FROM RED TO BLUE L'OREAL (FR) 2000-08-08 US claimed
EP-1011619-A1 DYEING COMPOSITION FOR KERATIN FIBRES L'OREAL (FR) 2000-06-28 EP claimed
WO-1999011231-A1 DYEING COMPOSITION FOR KERATIN FIBRES L'OREAL (FR) 1999-03-11 WO claimed
EP-0740931-B1 Compositions for dyeing keratinic fibers containing diaminopyrazoles, process for dyeing, diaminopyrazoles and process for their preparation OREAL (FR) 1997-08-20 EP claimed
WO-1996034591-A1 DIAMINOPYRAZOLE-CONTAINING COMPOSITIONS FOR COLOURING KERATIN FIBRES, COLOURING PROCESS, NOVEL DIAMINOPYRAZOLES AND METHOD FOR THEIR PREPARATION L'OREAL (FR) 1996-11-07 WO claimed
EP-0740931-A1 Compositions for dyeing keratinic fibers containing diaminopyrazoles, process for dyeing, diaminopyrazoles and process for their preparation L'OREAL (FR) 1996-11-06 EP claimed