Omeprazole Sulfone

Omeprazole Sulfone

SCHEMBL33721996

COc1ccc2[nH]c(S(=O)(=O)Cc3ncc(C)c(OC)c3C)nc2c1

nearest known ligand 0.85

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.85
KMT2A Q03164 5/20 0.52
ATP4A P20648 5/20 0.52
ATP4B P51164 5/20 0.52
ATP1A1 P05023 4/20 0.52
ATP1B1 P05026 4/20 0.52
ATP1A3 P13637 4/20 0.52
ATP1B2 P14415 4/20 0.52
ATP1A2 P50993 4/20 0.52
ATP1B3 P54709 4/20 0.52
FXYD2 P54710 4/20 0.52
ATP1A4 Q13733 4/20 0.52
ALDH1A1 P00352 4/20 0.52
WDR5 P61964 3/20 0.52
BRS3 P32247 2/20 0.52
DDAH1 O94760 2/20 0.52
ENGASE Q8NFI3 2/20 0.52
CYP1A2 P05177 2/20 0.52
MAPT P10636 2/20 0.52
CYP2C19 P33261 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Omeprazole Sulfone SCHEMBL29415504 1.00 CYP2C9 (0.85) CYP2C9KMT2AATP4AATP4BATP1A1
Omeprazole Sulfone SCHEMBL2340649 1.00 CYP2C9 (0.85) CYP2C9KMT2AATP4AATP4BATP1A1
Omeprazole Sulfone SCHEMBL28015857 0.99 CYP2C9 (0.83) CYP2C9KMT2AATP4AATP4BATP1A1
Omeprazole Sulfone SCHEMBL4950986 0.92 CYP2C9 (1.00) CYP2C9KMT2AATP4AATP4BATP1A1
SCHEMBL23988472 0.90 CYP2C9 (0.70) CYP2C9KMT2AATP4AATP4BATP1A1
SCHEMBL23988443 0.90 CYP2C9 (0.70) CYP2C9KMT2AATP4AATP4BATP1A1
SCHEMBL1477733 0.90 CYP2C9 (0.69) CYP2C9KMT2AATP4AATP4BATP1A1
SCHEMBL23988514 0.90 CYP2C9 (0.69) CYP2C9KMT2AATP4AATP4BATP1A1
SCHEMBL13645222 0.88 CYP2C9 (0.67) CYP2C9KMT2AATP4AATP4BATP1A1
SCHEMBL23988476 0.86 CYP2C9 (0.76) CYP2C9KMT2AATP4AATP4BATP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121779286-A Alpha-dideuteromethylation sulfone compound and synthetic method and application thereof 河南师范大学 2026-04-03 CN disclosed