Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 13/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371621 | 0.85 | GRM5 (0.48) | GRM5CNR2L3MBTL1NPC1RAB9A | |
| SCHEMBL3375215 | 0.85 | GRM5 (0.48) | GRM5CNR2L3MBTL1NPC1RAB9A | |
| SCHEMBL990298 | 0.85 | GRM5 (0.45) | GRM5CNR2L3MBTL1IDO1NPC1 | |
| SCHEMBL992315 | 0.85 | GRM5 (0.45) | GRM5CNR2L3MBTL1IDO1NPC1 | |
| SCHEMBL3376157 | 0.84 | GRM5 (0.46) | GRM5L3MBTL1NPC1RAB9A | |
| SCHEMBL3276845 | 0.81 | GRM5 (0.51) | GRM5L3MBTL1 | |
| SCHEMBL3276840 | 0.81 | GRM5 (0.51) | GRM5L3MBTL1 | |
| SCHEMBL4656464 | 0.81 | GRM5 (0.51) | GRM5L3MBTL1 | |
| SCHEMBL3276839 | 0.81 | GRM5 (0.51) | GRM5L3MBTL1 | |
| SCHEMBL3276822 | 0.81 | GRM5 (0.51) | GRM5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877365-B1 | ACETYLENE DERIVATIVES | NOVARTIS AG (CH) | 2010-11-10 | — | — | EP | claimed |