Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374154 | 0.91 | PTGDR2 (0.55) | PTGDR2AKR1B1 | |
| SCHEMBL2053697 | 0.90 | PTGDR2 (0.54) | PTGDR2AKR1B1 | |
| SCHEMBL2053814 | 0.90 | PTGDR2 (0.70) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL3373960 | 0.90 | PTGDR2 (0.70) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL2031573 | 0.88 | PTGDR2 (0.67) | PTGDR2AKR1B1 | |
| SCHEMBL3372368 | 0.87 | PTGDR2 (0.76) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL2052563 | 0.87 | PTGDR2 (0.71) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL3370170 | 0.81 | PTGDR2 (0.52) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL3375010 | 0.81 | PTGDR2 (0.57) | PTGDR2AKR1B1 | |
| SCHEMBL2049959 | 0.81 | PTGDR2 (1.00) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656347-B1 | SUBSTITUTED INDOLE DERIVATIVES FOR PHARMACEUTICAL COMPOSITION FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2010-10-13 | — | — | EP | claimed |