SCHEMBL337512

SCHEMBL337512

CCCCCCCCCCCCC(F)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 1.00
GPR84 Q9NQS5 7/20 0.59
FFAR1 O14842 2/20 0.59
LCK P06239 1/20 0.57
PPARD Q03181 1/20 0.57
ZDHHC20 Q5W0Z9 1/20 0.57
ZDHHC2 Q9UIJ5 1/20 0.57
ACE2 Q9BYF1 1/20 0.53
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48
FFAR4 Q5NUL3 1/20 0.48
CES2 O00748 1/20 0.48
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8694164 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL3408121 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL9292097 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL338043 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL337879 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL21808105 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL7461276 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL337289 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL9291062 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD
SCHEMBL9060844 1.00 MAPT (1.00) MAPTGPR84FFAR1LCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN claimed
CN-103826633-A Methylphenidate prodrugs, methods of making and using the same KEMPHARM INC 2014-05-28 CN claimed
US-4780319-A DRUG DELIVERY USING POLYORTHOESTERS COATINGS MERCK & CO., INC. (US) 1988-10-25 US claimed
WO-2022230929-A1 METHOD FOR DECOMPOSING POLYFLUOROCARBOXYLIC ACIDS AGC株式会社 2022-11-03 WO disclosed
CN-107261148-B Methylphenidate prodrugs, methods of making and using the same 凯姆制药公司 2021-07-13 CN disclosed
CN-105247024-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2018-08-10 CN disclosed
CN-105283529-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2018-08-10 CN disclosed
CN-105247025-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2017-12-01 CN disclosed
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN disclosed
CN-103826633-B Methylphenidate prodrugs, methods of making and using the same 凯姆制药公司 2017-05-24 CN disclosed
CN-104822810-B Comprising boroxin and amines to improve the lubricant compositions of fluoropolymer seal part compatibility 巴斯夫欧洲公司 2017-03-08 CN disclosed
US-5432534-A Reversible thermosensitive coloring composition, recording medium, recording method, and image display apparatus using the recording medium RICOH COMPANY, LTD. (JP) 1995-07-11 US disclosed
US-5395433-A Containing electron donor coloring and electron acceptor compounds which react to induce color formation; printers for computers, facsimile apparatus RICOH COMPANY, LTD. (JP) 1995-03-07 US disclosed
EP-0636134-A1 NOVEL ACYLATED PHOSPHOLIPID DRUGS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-02-01 EP disclosed
US-5296439-A Support with reversible thermosensitive coloring recording layer containing electron donor coloring compound, electron acceptor which reacts to induce color formation RICOH COMPANY, LTD. (JP) 1994-03-22 US disclosed
EP-0576015-A1 Method of reversible recording Ricoh Company, Ltd (JP) 1993-12-29 EP disclosed
WO-1993021191-A1 NOVEL ACYLATED PHOSPHOLIPID DRUGS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-10-28 WO disclosed
EP-0492628-A1 Reversible thermosensitive coloring composition, recording medium, recording method and image display apparatus using the recording medium Ricoh Company, Ltd (JP) 1992-07-01 EP disclosed
US-4780319-A DRUG DELIVERY USING POLYORTHOESTERS COATINGS MERCK & CO., INC. (US) 1988-10-25 US disclosed
US-4323547-A INVESTIGATING THE DINETICS OF HEART MUSCLE METABOLISM KERNFORSCHUNGSANLAGE JULICH GMBH (DE) 1982-04-06 US disclosed