⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19858587 | 0.81 | — | — | |
| SCHEMBL5270196 | 0.77 | — | — | |
| SCHEMBL13759743 | 0.72 | HTR2A (0.36) | — | |
| SCHEMBL12210679 | 0.70 | — | — | |
| SCHEMBL12128465 | 0.70 | — | — | |
| SCHEMBL28024136 | 0.69 | — | — | |
| SCHEMBL28117684 | 0.67 | — | — | |
| SCHEMBL28038371 | 0.67 | — | — | |
| SCHEMBL6017394 | 0.67 | — | — | |
| SCHEMBL13380547 | 0.67 | HTR2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097742-B2 | Water-soluble, surface-functionalized nanoparticle for bioconjugation via universal silane coupling | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-01-17 | — | — | US | disclosed |
| US-20080045736-A1 | Water-Soluble, Surface-Functionalized Nanoparticle for Bioconjugation Via Universal Silane Coupling | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-02-21 | — | — | US | disclosed |
| EP-1846421-A1 | WATER-SOLUBLE, SURFACE-FUNCTIONALIZED NANOPARTICLE FOR BIOCONJUGATION VIA UNIVERSAL SILANE COUPLING | Agency for Science, Technology and Research (SG) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006080895-A1 | WATER-SOLUBLE, SURFACE-FUNCTIONALIZED NANOPARTICLE FOR BIOCONJUGATION VIA UNIVERSAL SILANE COUPLING | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-08-03 | — | — | WO | disclosed |