Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.59 |
| ▸ | PDE2A | O00408 | 19/20 | 0.59 |
| ▸ | PDE4A | P27815 | 5/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.59 |
| ▸ | PDE6D | O43924 | 8/20 | 0.41 |
| ▸ | PDE6A | P16499 | 8/20 | 0.41 |
| ▸ | PDE6G | P18545 | 8/20 | 0.41 |
| ▸ | PDE6B | P35913 | 8/20 | 0.41 |
| ▸ | PDE6C | P51160 | 8/20 | 0.41 |
| ▸ | PDE6H | Q13956 | 8/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322789 | 0.76 | PDE10A (0.65) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL3322267 | 0.74 | PDE2A (1.00) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL3320945 | 0.73 | PDE2A (0.65) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL3320603 | 0.73 | PDE2A (1.00) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL3321865 | 0.73 | PDE2A (1.00) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL29371951 | 0.69 | PDGFRB (0.48) | — | |
| SCHEMBL15953378 | 0.68 | PDE2A (0.59) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL14774006 | 0.66 | PDE2A (0.62) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL3325266 | 0.65 | PDE10A (0.51) | PDE10APDE2APDE4APDE4BPDE4C | |
| SCHEMBL15953391 | 0.64 | PDE2A (0.56) | PDE10APDE2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054253-A1 | TRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES | BIOTIE THERAPIES GMBH (DE) | 2010-05-14 | — | — | WO | claimed |