SCHEMBL3377169

SCHEMBL3377169

CC(C)(C)OC(=O)NC1CC2CC2C1C=O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.39
BTK Q06187 1/20 0.39
F2R P25116 1/20 0.38
NFKB1 P19838 4/20 0.37
NFKB2 Q00653 4/20 0.37
RELA Q04206 4/20 0.37
GAA P10253 2/20 0.35
MAOB P27338 2/20 0.35
MAOA P21397 1/20 0.35
CTSK P43235 2/20 0.34
CYP2C9 P11712 1/20 0.34
HSD11B1 P28845 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31732240 0.81 KDM1A (0.41) KDM1ABTKF2RNFKB1NFKB2
SCHEMBL20090287 0.80 BTK (0.42) KDM1ABTKF2RNFKB1NFKB2
SCHEMBL22241781 0.80 BTK (0.42) KDM1ABTKF2RNFKB1NFKB2
SCHEMBL17852777 0.80 BTK (0.42) KDM1ABTKF2RNFKB1NFKB2
SCHEMBL17852773 0.80 BTK (0.42) KDM1ABTKF2RNFKB1NFKB2
SCHEMBL17852775 0.78 BTK (0.41) KDM1ABTKF2RNFKB1NFKB2
SCHEMBL22616376 0.77 BTK (0.47) KDM1ABTKNFKB1NFKB2RELA
SCHEMBL31566189 0.77 BTK (0.47) KDM1ABTKNFKB1NFKB2RELA
SCHEMBL27509490 0.76 BTK (0.49) KDM1ABTKF2RNFKB1NFKB2
SCHEMBL27510185 0.76 KDM1A (0.42) KDM1ABTKF2RNFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012000608-A2 NOVEL BETA-AMINOALDEHYDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR CHEMICAL USE AS REACTIVE INTERMEDIATES GLUESENKAMP KARL-HEINZ (DE) 2012-01-05 WO disclosed