Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381390 | 0.94 | HTR2C (0.33) | HRH3GAAALDH1A1HTR2CLMNA | |
| Hydrochloric Acid SCHEMBL3381040 | 0.87 | HRH3 (0.36) | HRH3GAAALDH1A1HTR2CLMNA | |
| Hydrochloric Acid SCHEMBL3381038 | 0.87 | HRH3 (0.36) | HRH3GAAALDH1A1HTR2CLMNA | |
| SCHEMBL3377365 | 0.86 | HRH3 (0.47) | HRH3GAALMNAKCNH2MCHR1 | |
| SCHEMBL3375226 | 0.82 | HRH3 (0.42) | HRH3LMNABRD4 | |
| SCHEMBL3375070 | 0.82 | HRH3 (0.43) | HRH3GAAALDH1A1TDP1LMNA | |
| SCHEMBL3375072 | 0.82 | HRH3 (0.43) | HRH3GAAALDH1A1TDP1LMNA | |
| Hydrochloric Acid SCHEMBL3380360 | 0.81 | USP2 (0.35) | HRH3ALDH1A1HTR2CFFAR1ADRB2 | |
| Hydrochloric Acid SCHEMBL3380364 | 0.81 | USP2 (0.35) | HRH3ALDH1A1HTR2CFFAR1ADRB2 | |
| SCHEMBL3378689 | 0.80 | HRH3 (0.39) | HRH3ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |