Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377605 | 1.00 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3377596 | 1.00 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL4779781 | 1.00 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3373310 | 0.79 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3373306 | 0.79 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL21935941 | 0.78 | — | — | |
| SCHEMBL3375788 | 0.77 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3376348 | 0.77 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3373002 | 0.77 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3375784 | 0.77 | KCNH2 (0.44) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987040-B1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-11-10 | — | — | EP | disclosed |