Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253483 | 0.86 | KCNH2 (0.54) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3378200 | 0.85 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL16649510 | 0.84 | KCNH2 (0.53) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3377361 | 0.84 | KCNH2 (0.69) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3377367 | 0.84 | KCNH2 (0.69) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3376441 | 0.82 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3376444 | 0.82 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3373011 | 0.82 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3373008 | 0.82 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3377415 | 0.75 | KCNH2 (0.44) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987040-B1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-11-10 | — | — | EP | claimed |