SCHEMBL33779

SCHEMBL33779

C=C(C)C(=O)OC(C)C#N

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28158416 0.96 TSHR (0.44) TSHRALDH1A1
Methacrylic Acid SCHEMBL27996428 0.94 TSHR (0.42) TSHRALDH1A1
Cyanamide SCHEMBL28026069 0.94 TSHR (0.42) TSHRALDH1A1TDP1
Carbamic Acid SCHEMBL28329177 0.92 TSHR (0.41) TSHRALDH1A1TDP1
Phosphonic Acid SCHEMBL28048734 0.92 TSHR (0.41) TSHRALDH1A1
Acrylic Acid SCHEMBL28859613 0.89 TSHR (0.39) TSHRALDH1A1
SCHEMBL29157304 0.88 TSHR (0.38) TSHRALDH1A1
SCHEMBL9471688 0.88 TSHR (0.38) TSHRALDH1A1
Acetoacetic Acid SCHEMBL28209597 0.86 TSHR (0.41) TSHRALDH1A1
SCHEMBL8217476 0.85 TSHR (0.40) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5597 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4316470-B1 NEW FORMULATIONS BETAGENON AB (SE) 2026-04-29 EP claimed
EP-4539825-A1 BILAYER TABLETS OF VALSARTAN AND INDAPAMIDE KRKA, D.D., Novo Mesto (SI) 2025-04-23 EP claimed
CN-118806764-A Sustained release formulations and methods of use thereof 珐博进(中国)医药技术开发有限公司 2024-10-22 CN claimed
EP-4316470-A2 NEW FORMULATIONS Betagenon AB (SE) 2024-02-07 EP claimed
CN-117374380-A Single-ion conductor polymer electrolyte and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2024-01-09 CN claimed
WO-2023247435-A1 BILAYER TABLETS OF VALSARTAN AND INDAPAMIDE KRKA, D.D., NOVO MESTO (SI) 2023-12-28 WO claimed
EP-4295839-A1 COMBINATION OF VALSARTAN AND INDAPAMIDE KRKA, d.d., Novo mesto (SI) 2023-12-27 EP claimed
EP-4045038-B1 NEW FORMULATIONS OF 4-CHLORO-N-[2-[(4-CHLOROPHENYL)METHYL]-3-OXO-1,2,4-THIADIAZOL-5-YL]BENZAMIDE BETAGENON AB (SE) 2023-12-06 EP claimed
US-20230270687-A1 HOMEOPATHIC ANTIVIRAL HYDROGEL PATCHES JSIC Laboratories, LLC 2023-08-31 US claimed
US-11691954-B2 Formulations BETAGENON AB (SE) 2023-07-04 US claimed
WO-2004026283-A1 SEQUESTERING SUBUNIT AND RELATED COMPOSITIONS AND METOHDS ALPHARMA, INC. (US) 2004-04-01 WO claimed
WO-2003082204-A2 SUSTAINED-RELEASE GEL COATED COMPOSITIONS EURO-CELTIQUE S.A. (LU) 2003-10-09 WO claimed
US-20030190362-A1 Sustained-release gel coated compositions PURDUE PHARMA L.P. 2003-10-09 US claimed
US-20030143269-A1 Tamper-resistant oral opioid agonist formulations PURDUE PHARMA L.P. 2003-07-31 US claimed
EP-1299104-A1 TAMPER-RESISTANT ORAL OPIOID AGONIST FORMULATIONS Euro-Celtique, S.A. (LU) 2003-04-09 EP claimed
US-20020164371-A1 Press coated, pulsatile drug delivery system suitable for oral administration IMPAX PHARMACEUTICALS INC. 2002-11-07 US claimed
WO-2001058451-A1 TAMPER-RESISTANT ORAL OPIOID AGONIST FORMULATIONS EURO-CELTIQUE, S.A. (LU) 2001-08-16 WO claimed
US-6143322-A PAIN THERAPY PURDUE PHARMA L.P. (US) 2000-11-07 US claimed
US-5958459-A SOLID ORAL DOSAGE FORM CONSISTING OF INERT PHARMACEUTICAL BEADS COATED WITH OPIOID ANALGESIC AND OVERCOATED WITH CONTROLLED-RELEASE COATING PURDUE PHARMA L.P. (US) 1999-09-28 US claimed
EP-0183989-A2 Fluorine-containing graft copolymer and adhesive and composite membrane made thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-06-11 EP claimed