Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.69 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | HTR2B | P41595 | 4/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381182 | 0.93 | SLC6A4 (0.75) | SLC6A4HTR2CHTR2B | |
| SCHEMBL2286691 | 0.85 | SLC6A4 (0.85) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL2282901 | 0.84 | SLC6A4 (0.84) | SLC6A4HTR2CHTR2B | |
| SCHEMBL2288146 | 0.83 | SLC6A4 (0.73) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL2282467 | 0.82 | SLC6A4 (1.00) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL2281656 | 0.80 | SLC6A4 (1.00) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL2289062 | 0.78 | SLC6A4 (1.00) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL2287686 | 0.78 | SLC6A4 (1.00) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL2282653 | 0.77 | SLC6A4 (0.75) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL2286059 | 0.76 | SLC6A4 (1.00) | SLC6A4HTR2CHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | claimed |